Graves’ ophthalmopathy: low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts

OBJECTIVE: Graves’ ophthalmopathy (GO) is an autoimmune disease that leads to ocular proptosis caused by fat accumulation and inflammation, and the main treatment is corticosteroid therapy. Retinoid acid receptor-alpha (RARα) seems to be associated with inflammation and adipocyte differentiation. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Cury, Sarah Santiloni, Oliveira, Miriane, Síbio, Maria Teresa, Clara, Sueli, Luvizotto, Renata De Azevedo Melo, Conde, Sandro, Jorge, Edson Nacib, Nunes, Vania dos Santos, Nogueira, Célia Regina, Mazeto, Gláucia Maria Ferreira da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118777/
https://www.ncbi.nlm.nih.gov/pubmed/29791662
http://dx.doi.org/10.20945/2359-3997000000044

Ejemplares similares

Ejemplares similares