Cargando…

Strong Selection of a Few Dominant CD8 Clones in a TLR7-Dependent Autoimmune Mouse Model

Systemic lupus is characterized by the expansion of a self-reactive repertoire of B cells and CD4 cells that together promote IgG Ab production against common nuclear Ags. Although several studies have suggested roles for CD8(+) T cells in lupus, the full contribution of these lymphocytes to disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Morawski, Peter A., Bolland, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118847/
https://www.ncbi.nlm.nih.gov/pubmed/31356154
http://dx.doi.org/10.4049/immunohorizons.1800082