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Strong Selection of a Few Dominant CD8 Clones in a TLR7-Dependent Autoimmune Mouse Model
Systemic lupus is characterized by the expansion of a self-reactive repertoire of B cells and CD4 cells that together promote IgG Ab production against common nuclear Ags. Although several studies have suggested roles for CD8(+) T cells in lupus, the full contribution of these lymphocytes to disease...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118847/ https://www.ncbi.nlm.nih.gov/pubmed/31356154 http://dx.doi.org/10.4049/immunohorizons.1800082 |