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The use of aromatase inhibitors in boys with short stature: what to know before prescribing?

Aromatase is a cytochrome P450 enzyme (CYP19A1 isoform) able to catalyze the conversion of androgens to estrogens. The aromatase gene mutations highlighted the action of estrogen as one of the main regulators of bone maturation and closure of bone plate. The use of aromatase inhibitors (AI) in boys...

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Detalles Bibliográficos
Autores principales:	Linardi, Alessandra, Damiani, Durval, Longui, Carlos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Endocrinologia e Metabologia 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118929/ https://www.ncbi.nlm.nih.gov/pubmed/28977209 http://dx.doi.org/10.1590/2359-3997000000284

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