Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder

Major depressive disorder (MDD) refers to a widespread psychiatric disorder. Astrocytes play a pivotal role in regulating inflammation which is a well-acknowledged key component in depression pathogenesis. However, the effects of the neuroinflammation-inducing A1-like astrocytes on MDD are still unk...

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Detalles Bibliográficos
Autores principales: Cong, Ting, Sun, Ye, Zhou, Yitong, Wu, Haikuo, Li, Liya, Chu, Zhenchen, Chen, Xue, Li, Jinying, Zhao, Danmei, Wang, Yanfang, Liu, Yingxin, Yin, Shengming, Xiao, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119044/
https://www.ncbi.nlm.nih.gov/pubmed/36670238
http://dx.doi.org/10.1007/s11064-023-03857-4

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