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Dysregulation of astrocytic Ca(2+) signaling and gliotransmitter release in mouse models of α-synucleinopathies

α-Synuclein is a major component of Lewy bodies (LB) and Lewy neurites (LN) appearing in the postmortem brain of Parkinson's disease (PD) and other α-synucleinopathies. While most studies of α-synucleinopathies have focused on neuronal and synaptic alterations as well as dysfunctions of the ast...

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Detalles Bibliográficos
Autores principales: Nanclares, Carmen, Poynter, Jonah, Martell-Martinez, Hector A., Vermilyea, Scott, Araque, Alfonso, Kofuji, Paulo, Lee, Michael K., Covelo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119048/
https://www.ncbi.nlm.nih.gov/pubmed/36764943
http://dx.doi.org/10.1007/s00401-023-02547-3