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Glucocorticoid activation of anti-inflammatory macrophages protects against insulin resistance

Insulin resistance (IR) during obesity is linked to adipose tissue macrophage (ATM)-driven inflammation of adipose tissue. Whether anti-inflammatory glucocorticoids (GCs) at physiological levels modulate IR is unclear. Here, we report that deletion of the GC receptor (GR) in myeloid cells, including...

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Detalles Bibliográficos
Autores principales:	Caratti, Giorgio, Stifel, Ulrich, Caratti, Bozhena, Jamil, Ali J. M., Chung, Kyoung-Jin, Kiehntopf, Michael, Gräler, Markus H., Blüher, Matthias, Rauch, Alexander, Tuckermann, Jan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119112/ https://www.ncbi.nlm.nih.gov/pubmed/37080971 http://dx.doi.org/10.1038/s41467-023-37831-z

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