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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
PURPOSE: Ongoing angiogenesis renders the tumor endothelium unresponsive to inflammatory cytokines and interferes with adhesion of leukocytes, resulting in escape from immunity. This process is referred to as tumor endothelial cell anergy. We aimed to investigate whether anti-angiogenic agents can o...
Autores principales: | Nowak-Sliwinska, Patrycja, van Beijnum, Judy R., Griffioen, Christian J., Huinen, Zowi R., Sopesens, Nadine Grima, Schulz, Ralph, Jenkins, Samir V., Dings, Ruud P. M., Groenendijk, Floris H., Huijbers, Elisabeth J. M., Thijssen, Victor L. J. L., Jonasch, Eric, Vyth-Dreese, Florry A., Jordanova, Ekaterina S., Bex, Axel, Bernards, René, de Gruijl, Tanja D., Griffioen, Arjan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119234/ https://www.ncbi.nlm.nih.gov/pubmed/36459240 http://dx.doi.org/10.1007/s10456-022-09863-4 |
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