Cargando…

Secretin modulates appetite via brown adipose tissue-brain axis

PURPOSE: Secretin activates brown adipose tissue (BAT) and induces satiation in both mice and humans. However, the exact brain mechanism of this satiety inducing, secretin-mediated gut-BAT-brain axis is largely unknown. METHODS AND RESULTS: In this placebo-controlled, single-blinded neuroimaging stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Lihua, Laurila, Sanna, Lahesmaa, Minna, Rebelos, Eleni, Virtanen, Kirsi A., Schnabl, Katharina, Klingenspor, Martin, Nummenmaa, Lauri, Nuutila, Pirjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119257/ https://www.ncbi.nlm.nih.gov/pubmed/36764966 http://dx.doi.org/10.1007/s00259-023-06124-4

Ejemplares similares

Novel effects of the gastrointestinal hormone secretin on cardiac metabolism and renal function
por: Laurila, Sanna, et al.
Publicado: (2022)

Pleiotropic Effects of Secretin: A Potential Drug Candidate in the Treatment of Obesity?
por: Laurila, Sanna, et al.
Publicado: (2021)

Thermogenic Capacity of Human Supraclavicular Brown Fat and Cold-Stimulated Brain Glucose Metabolism
por: U-Din, Mueez, et al.
Publicado: (2023)

Regulation of human brown adipose tissue by adenosine and A(2A) receptors – studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT
por: Lahesmaa, Minna, et al.
Publicado: (2018)

Brain insulin sensitivity is linked to body fat distribution—the positron emission tomography perspective
por: Rebelos, Eleni, et al.
Publicado: (2020)

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp—A Study in Finns
por: Rebelos, Eleni, et al.
Publicado: (2021)

Circulating neurofilament is linked with morbid obesity, renal function, and brain density
por: Rebelos, Eleni, et al.
Publicado: (2022)

[(11)C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue
por: Sun, Lihua, et al.
Publicado: (2022)

Neural Circuits for Cognitive Appetite Control in Healthy and Obese Individuals: An fMRI Study
por: Tuulari, Jetro J., et al.
Publicado: (2015)

Brain substrate metabolism and ß‐cell function in humans: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow‐up
por: Rebelos, Eleni, et al.
Publicado: (2018)

Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
por: Rebelos, Eleni, et al.
Publicado: (2021)

Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
por: Dieckmann, Sebastian, et al.
Publicado: (2020)

Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

Changes in electrocardiogram parameters during acute nonshivering cold exposure and associations with brown adipose tissue activity, plasma catecholamine levels, and brachial blood pressure in healthy adults
por: Raiko, Juho R. H., et al.
Publicado: (2021)

Human brown adipose tissue [(15)O]O(2) PET imaging in the presence and absence of cold stimulus
por: u Din, Mueez, et al.
Publicado: (2016)

Hepatic Positron Emission Tomography: Applications in Metabolism, Haemodynamics and Cancer
por: Honka, Miikka-Juhani, et al.
Publicado: (2022)

The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles
por: Sato, Keisaku, et al.
Publicado: (2017)

Obesity risk is associated with brain glucose uptake and insulin resistance
por: Pekkarinen, Laura, et al.
Publicado: (2022)

Brain Glucose Metabolism in Health, Obesity, and Cognitive Decline—Does Insulin Have Anything to Do with It? A Narrative Review
por: Rebelos, Eleni, et al.
Publicado: (2021)

Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain
por: Pak, Kyoungjune, et al.
Publicado: (2022)

Author Correction: The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles
por: Sato, Keisaku, et al.
Publicado: (2018)

Secretin
Publicado: (1908)

Preoperative brain μ-opioid receptor availability predicts weight development following bariatric surgery in women
por: Karlsson, Henry K., et al.
Publicado: (2021)

Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery
por: Karlsson, Henry K., et al.
Publicado: (2021)

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
por: Hirvonen, Jussi, et al.
Publicado: (2011)

Fat Grafting Can Induce Browning of White Adipose Tissue
por: Hoppela, Erika, et al.
Publicado: (2018)

μ-opioid receptor system mediates reward processing in humans
por: Nummenmaa, Lauri, et al.
Publicado: (2018)

μ-opioid receptor availability is associated with sex drive in human males
por: Nummenmaa, Lauri, et al.
Publicado: (2021)

Opposing Actions of Adrenocorticotropic Hormone and Glucocorticoids on UCP1-Mediated Respiration in Brown Adipocytes
por: Schnabl, Katharina, et al.
Publicado: (2019)

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study
por: Honka, Miikka-Juhani, et al.
Publicado: (2018)

Brown Adipose Tissue Energy Metabolism in Humans
por: Carpentier, André C., et al.
Publicado: (2018)

Obesity-associated Blunted Subcutaneous Adipose Tissue Blood Flow After Meal Improves After Bariatric Surgery
por: Saari, Teemu, et al.
Publicado: (2022)

On the Treatment of Diabetes with Secretin
por: Charles, J. R.
Publicado: (1906)

Editorial: Brown Adipose Tissue: From Heat Production in Rodents to Metabolic Health in Humans
por: Chondronikola, Maria, et al.
Publicado: (2021)

Decreased insulin‐stimulated brown adipose tissue glucose uptake after short‐term exercise training in healthy middle‐aged men
por: Motiani, Piryanka, et al.
Publicado: (2017)

Dorsal Striatum and Its Limbic Connectivity Mediate Abnormal Anticipatory Reward Processing in Obesity
por: Nummenmaa, Lauri, et al.
Publicado: (2012)

Origin of Secretin Receptor Precedes the Advent of Tetrapoda: Evidence on the Separated Origins of Secretin and Orexin
por: Tam, Janice K. V., et al.
Publicado: (2011)

Renal Perfusion, Oxygenation and Metabolism: The Role of Imaging
por: Päivärinta, Johanna, et al.
Publicado: (2023)

The Treatment of Glycosuria by Trypsin and Secretin
por: Clutterbuck, L. A.
Publicado: (1907)

Cannot write session to /tmp/vufind_sessions/sess_phcaq9tj80e2nn04eluhcku16i