Cargando…

Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription

Precise and specific spatiotemporal domains of gene expression regulation are critical for embryonic development. Recent studies have identified GLTSCR1 as a gene transcriptional elongation regulator in cancer research. However, the function of GLTSCR1, especially in embryonic development, remains p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Fengyan, Yang, Beibei, Chen, Yan, Liu, Lu, Cheng, Xiaoqing, Huang, Jiaqi, Zhou, Ke, Zhang, Dandan, Xu, Enping, Lai, Maode, Lv, Bingjian, Cheng, Hongqiang, Zhang, Honghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119265/ https://www.ncbi.nlm.nih.gov/pubmed/36745292 http://dx.doi.org/10.1007/s10456-023-09869-6

Ejemplares similares

GLTSCR1 coordinates alternative splicing and transcription elongation of ZO1 to regulate colorectal cancer progression
por: Han, Fengyan, et al.
Publicado: (2022)

GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis
por: Han, Fengyan, et al.
Publicado: (2019)

Natural antisense transcript of natriuretic peptide precursor A (NPPA): structural organization and modulation of NPPA expression
por: Annilo, Tarmo, et al.
Publicado: (2009)

GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer
por: Kim, Jee-Youn, et al.
Publicado: (2015)

The nucleolar protein GLTSCR2 is required for efficient viral replication
por: Wang, Peng, et al.
Publicado: (2016)

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF
por: Lee, Sun, et al.
Publicado: (2016)

HOTAIRM1 as a potential biomarker for diagnosis of colorectal cancer functions the role in the tumour suppressor
por: Wan, Ledong, et al.
Publicado: (2016)

IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells
por: Cao, Hui, et al.
Publicado: (2016)

GDF15 promotes EMT and metastasis in colorectal cancer
por: Li, Chen, et al.
Publicado: (2015)

Cellular protein GLTSCR2: A valuable target for the development of broad-spectrum antivirals
por: Li, Cui-Cui, et al.
Publicado: (2017)

Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer
por: Li, Chen, et al.
Publicado: (2016)

Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
por: Kalt, Inna, et al.
Publicado: (2012)

Association of Common Variants in NPPA and NPPB with Circulating Natriuretic Peptides and Blood Pressure
por: Newton-Cheh, Christopher, et al.
Publicado: (2009)

Structure and function of the Nppa–Nppb cluster locus during heart development and disease
por: Man, Joyce, et al.
Publicado: (2018)

Case report: Mutation in NPPA gene as a cause of fibrotic atrial myopathy
por: Silva Cunha, Pedro, et al.
Publicado: (2023)

Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer
por: Sun, Aijun, et al.
Publicado: (2021)

The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
por: Wang, Xue, et al.
Publicado: (2018)

Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils
por: Yu, Hongfei, et al.
Publicado: (2022)

ENO2 Promotes Colorectal Cancer Metastasis by Interacting with the LncRNA CYTOR and Activating YAP1-Induced EMT
por: Lv, Chunwei, et al.
Publicado: (2022)

Association between NPPA promoter methylation and hypertension: results from Gusu cohort and replication in an independent sample
por: Li, Jing, et al.
Publicado: (2020)

Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness
por: Chen, Chaoyi, et al.
Publicado: (2022)

2-NPPA Mitigates Osteoclastogenesis via Reducing TRAF6-Mediated c-fos Expression
por: Chen, Zhihao, et al.
Publicado: (2021)

PMEPA1 induces EMT via a non‐canonical TGF‐β signalling in colorectal cancer
por: Zhang, Lei, et al.
Publicado: (2019)

The cancer secretome: a reservoir of biomarkers
por: Xue, Hua, et al.
Publicado: (2008)

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug
por: Song, Ping, et al.
Publicado: (2016)

Serum Atrial Natriuretic Peptide, NPPA Promoter Methylation, and Cardiovascular Disease: A 10-year Follow-Up Study in Chinese Adults
por: Chen, Linan, et al.
Publicado: (2022)

A transcriptome anatomy of human colorectal cancers
por: Lü, Bingjian, et al.
Publicado: (2006)

ASA Status, NPPA/NPPB Haplotype and Coronary Artery Disease Have an Impact on BNP/NT-proBNP Plasma Levels
por: Hahn, Markus, et al.
Publicado: (2022)

Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG
por: Deng, Jingwen, et al.
Publicado: (2023)

THBS2 is a Potential Prognostic Biomarker in Colorectal Cancer
por: Wang, Xue, et al.
Publicado: (2016)

TSVdb: a web-tool for TCGA splicing variants analysis
por: Sun, Wenjie, et al.
Publicado: (2018)

Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N(6)‐methyladenosine methylation through methyltransferase‐like 14
por: Wang, Shuo, et al.
Publicado: (2021)

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs
por: Zhou, Dan, et al.
Publicado: (2015)

Antitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) on MDA-MB-231 cells: in vitro and in vivo
por: Duan, Xiao-Chuan, et al.
Publicado: (2018)

A novel cell-based assay for dynamically detecting neutrophil extracellular traps-induced lung epithelial injuries
por: Lv, Dandan, et al.
Publicado: (2020)

Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer
por: Cheng, Xiaoqing, et al.
Publicado: (2022)

The synergistic antitumor activity of 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) and anti-PD-L1 antibody inducing immunogenic cell death
por: Duan, Xiao-Chuan, et al.
Publicado: (2021)

Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster
por: Del Greco M., Fabiola, et al.
Publicado: (2011)

MEF2C loss-of-function mutation contributes to congenital heart defects
por: Qiao, Xiao-Hui, et al.
Publicado: (2017)

An infant with congenital heart defects and proteinuria: a case report
por: Liu, Dandan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3jaj1ek50v7a890cb8ko8o44if