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Molecular characterization of AIFM2/FSP1 inhibition by iFSP1-like molecules

Ferroptosis is a form of cell death characterized by phospholipid peroxidation, where numerous studies have suggested that the induction of ferroptosis is a therapeutic strategy to target therapy refractory cancer entities. Ferroptosis suppressor protein 1 (FSP1), an NAD(P)H-ubiquinone reductase, is...

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Detalles Bibliográficos
Autores principales: Xavier da Silva, Thamara Nishida, Schulte, Clemens, Alves, Ariane Nunes, Maric, Hans Michael, Friedmann Angeli, José Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119282/
https://www.ncbi.nlm.nih.gov/pubmed/37080964
http://dx.doi.org/10.1038/s41419-023-05787-z