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Design of C(1)-symmetric tridentate ligands for enantioselective dearomative [3 + 2] annulation of indoles with aminocyclopropanes

Chiral polycyclic indolines are widely present in natural products and have become the focus of extensive synthetic efforts. Here, we show the catalytic asymmetric dearomative [3 + 2] annulation of indoles with donor-acceptor aminocyclopropanes to construct tricyclic indolines. Key to the success of...

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Detalles Bibliográficos
Autores principales: Wang, Hai-Xia, Yang, Chun, Xue, Bai-Yu, Xie, Ming-Sheng, Tian, Yin, Peng, Cheng, Guo, Hai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119320/
https://www.ncbi.nlm.nih.gov/pubmed/37080997
http://dx.doi.org/10.1038/s41467-023-38059-7