RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis

Cellular senescence provides a protective barrier against tumorigenesis in precancerous or normal tissues upon distinct stressors. However, the detailed mechanisms by which tumor cells evade premature senescence to malignant progression remain largely elusive. Here we reported that RBM4 adversely im...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Zhang, Wenjing, Chen, Dan, Yang, Quan, Sun, Siwen, Dai, Zhenwei, Li, Zhengzheng, Liang, Xuemei, Chen, Chaoqun, Jiao, Yuexia, Zhi, Lili, Zhao, Lianmei, Zhang, Jinrui, Liu, Xuefeng, Zhao, Jinyao, Li, Man, Wang, Yang, Qi, Yangfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119322/
https://www.ncbi.nlm.nih.gov/pubmed/37080995
http://dx.doi.org/10.1038/s41392-023-01367-x

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