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TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication

Coronaviruses are positive-strand RNA viruses with 3′ polyadenylated genomes and subgenomic transcripts. The lengths of the viral poly(A) tails change during infection by mechanisms that remain poorly understood. Here, we use a splint-ligation method to measure the poly(A) tail length and poly(A) te...

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Detalles Bibliográficos
Autores principales:	Gupta, Ankit, Li, Yin, Chen, Shih-Heng, Papas, Brian N., Martin, Negin P., Morgan, Marcos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119532/ https://www.ncbi.nlm.nih.gov/pubmed/37085578 http://dx.doi.org/10.1038/s42003-023-04814-1

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