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Caffeic acid, but not ferulic acid, inhibits macrophage pyroptosis by directly blocking gasdermin D activation

Regulated pyroptosis is critical for pathogen elimination by inducing infected cell rupture and pro‐inflammatory cytokines secretion, while overwhelmed pyroptosis contributes to organ dysfunction and pathological inflammatory response. Caffeic acid (CA) and ferulic acid (FA) are both well‐known anti...

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Detalles Bibliográficos
Autores principales: Liu, Mingjiang, Liu, Dandan, Yu, Chenglong, Fan, Hua hao, Zhao, Xin, Wang, Huiwen, Zhang, Chi, Zhang, Minxia, Bo, Ruonan, He, Shasha, Wang, Xuerui, Jiang, Hui, Guo, Yuhong, Li, Jingui, Xu, Xiaolong, Liu, Qingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119582/
https://www.ncbi.nlm.nih.gov/pubmed/37090118
http://dx.doi.org/10.1002/mco2.255

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