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Risk factors and survival analysis of haemodialysis complicated with infective endocarditis
The clinical features and risk factors for survival time were analysed in haemodialysis patients complicated with infective endocarditis. A total of 101 infective endocarditis (IE) patients treated at Hangzhou First People's Hospital, from January 1, 2012, to April 1, 2022, were included in the...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119664/ https://www.ncbi.nlm.nih.gov/pubmed/37090071 http://dx.doi.org/10.3892/etm.2023.11902 |
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author | He, Ya-Jing Ye, Cun-Si Xu, Ke-Yang Yang, Li-Li Wang, Kai-Le Wang, Xiao-Mei Li, Mei-Yu Wu, Yu Ying, Qi-Su Wang, Ming Quan, Shi-Jian Yang, Xiu |
author_facet | He, Ya-Jing Ye, Cun-Si Xu, Ke-Yang Yang, Li-Li Wang, Kai-Le Wang, Xiao-Mei Li, Mei-Yu Wu, Yu Ying, Qi-Su Wang, Ming Quan, Shi-Jian Yang, Xiu |
author_sort | He, Ya-Jing |
collection | PubMed |
description | The clinical features and risk factors for survival time were analysed in haemodialysis patients complicated with infective endocarditis. A total of 101 infective endocarditis (IE) patients treated at Hangzhou First People's Hospital, from January 1, 2012, to April 1, 2022, were included in the present study. Baseline demographic data and laboratory data were collected for statistical analysis of risk factors and survival time in the IE with haemodialysis group (HD-IE group, n=15) and the IE without haemodialysis group (NHD-IE group, n=86). Haemoglobin, red blood cells, C-reactive protein, procalcitonin, serum albumin, diabetes, invasive procedures, positive blood bacteria culture, heart valve calcification ratio, and left ventricular ejection fraction level were risk factors for infective endocarditis complicated with haemodialysis (P<0.05). Compared with the NHD-IE group, the HD-IE group had an obviously increased risk of mortality (χ(2)=6.323, P=0.012). The univariate Cox regression analysis showed that age, haemoglobin, red blood cells, serum albumin, left ventricular ejection score, longest vegetation diameter, combined hypotension and diabetes were risk factors for death; furthermore, multivariate Cox regression showed that age (HR=1.187, P=0.015), combined hypotension (HR=0.921, P=0.025) and the longest vegetation diameter (HR=9.191, P=0.004) were independent risk factors affecting the survival of patients. Collectively, the present study revealed that the mortality rate of HD-IE patients was higher than that of NHD-IE patients. Older age, hypotension, and the longest vegetation diameter were independent risk factors affecting the survival of patients. For HD-IE patients, active and effective antibiotic treatment or surgical treatment should be strongly recommended. |
format | Online Article Text |
id | pubmed-10119664 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-101196642023-04-22 Risk factors and survival analysis of haemodialysis complicated with infective endocarditis He, Ya-Jing Ye, Cun-Si Xu, Ke-Yang Yang, Li-Li Wang, Kai-Le Wang, Xiao-Mei Li, Mei-Yu Wu, Yu Ying, Qi-Su Wang, Ming Quan, Shi-Jian Yang, Xiu Exp Ther Med Articles The clinical features and risk factors for survival time were analysed in haemodialysis patients complicated with infective endocarditis. A total of 101 infective endocarditis (IE) patients treated at Hangzhou First People's Hospital, from January 1, 2012, to April 1, 2022, were included in the present study. Baseline demographic data and laboratory data were collected for statistical analysis of risk factors and survival time in the IE with haemodialysis group (HD-IE group, n=15) and the IE without haemodialysis group (NHD-IE group, n=86). Haemoglobin, red blood cells, C-reactive protein, procalcitonin, serum albumin, diabetes, invasive procedures, positive blood bacteria culture, heart valve calcification ratio, and left ventricular ejection fraction level were risk factors for infective endocarditis complicated with haemodialysis (P<0.05). Compared with the NHD-IE group, the HD-IE group had an obviously increased risk of mortality (χ(2)=6.323, P=0.012). The univariate Cox regression analysis showed that age, haemoglobin, red blood cells, serum albumin, left ventricular ejection score, longest vegetation diameter, combined hypotension and diabetes were risk factors for death; furthermore, multivariate Cox regression showed that age (HR=1.187, P=0.015), combined hypotension (HR=0.921, P=0.025) and the longest vegetation diameter (HR=9.191, P=0.004) were independent risk factors affecting the survival of patients. Collectively, the present study revealed that the mortality rate of HD-IE patients was higher than that of NHD-IE patients. Older age, hypotension, and the longest vegetation diameter were independent risk factors affecting the survival of patients. For HD-IE patients, active and effective antibiotic treatment or surgical treatment should be strongly recommended. D.A. Spandidos 2023-03-21 /pmc/articles/PMC10119664/ /pubmed/37090071 http://dx.doi.org/10.3892/etm.2023.11902 Text en Copyright: © He et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles He, Ya-Jing Ye, Cun-Si Xu, Ke-Yang Yang, Li-Li Wang, Kai-Le Wang, Xiao-Mei Li, Mei-Yu Wu, Yu Ying, Qi-Su Wang, Ming Quan, Shi-Jian Yang, Xiu Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title | Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title_full | Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title_fullStr | Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title_full_unstemmed | Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title_short | Risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
title_sort | risk factors and survival analysis of haemodialysis complicated with infective endocarditis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119664/ https://www.ncbi.nlm.nih.gov/pubmed/37090071 http://dx.doi.org/10.3892/etm.2023.11902 |
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