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Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins

Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that collagen9a1c ( col9a1c ) gene product is...

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Autores principales: Nakagawa, Hibiki, Aramaki, Toshihiro, Kondo, Shigeru, Kuroda, Junpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119692/
https://www.ncbi.nlm.nih.gov/pubmed/37090155
http://dx.doi.org/10.17912/micropub.biology.000747
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author Nakagawa, Hibiki
Aramaki, Toshihiro
Kondo, Shigeru
Kuroda, Junpei
author_facet Nakagawa, Hibiki
Aramaki, Toshihiro
Kondo, Shigeru
Kuroda, Junpei
author_sort Nakagawa, Hibiki
collection PubMed
description Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that collagen9a1c ( col9a1c ) gene product is essential for the regular arrangement of actinotrichia using col9a1c -knockout zebrafish. Here, we examined the localization pattern of the EGFP-tagged Col9a1c protein in the fins to understand its role in the arrangement of actinotrichia. We found that EGFP-Col9a1c specifically localizes to actinotrichia.
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spelling pubmed-101196922023-04-22 Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins Nakagawa, Hibiki Aramaki, Toshihiro Kondo, Shigeru Kuroda, Junpei MicroPubl Biol Findings Previously Not Shown Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that collagen9a1c ( col9a1c ) gene product is essential for the regular arrangement of actinotrichia using col9a1c -knockout zebrafish. Here, we examined the localization pattern of the EGFP-tagged Col9a1c protein in the fins to understand its role in the arrangement of actinotrichia. We found that EGFP-Col9a1c specifically localizes to actinotrichia. Caltech Library 2023-04-07 /pmc/articles/PMC10119692/ /pubmed/37090155 http://dx.doi.org/10.17912/micropub.biology.000747 Text en Copyright: © 2023 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Findings Previously Not Shown
Nakagawa, Hibiki
Aramaki, Toshihiro
Kondo, Shigeru
Kuroda, Junpei
Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title_full Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title_fullStr Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title_full_unstemmed Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title_short Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
title_sort collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins
topic Findings Previously Not Shown
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119692/
https://www.ncbi.nlm.nih.gov/pubmed/37090155
http://dx.doi.org/10.17912/micropub.biology.000747
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