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Therapies in Stiff-Person Syndrome: Advances and Future Prospects Based on Disease Pathophysiology

Among the glutamic acid decarboxylase (GAD)-antibody–spectrum disorders, the most common phenotypic subset is the stiff-person syndrome (SPS), caused by impaired GABAergic inhibitory neurotransmission and autoimmunity characterized by very high titers of GAD antibodies and increased GAD-IgG intrathe...

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Detalles Bibliográficos
Autor principal: Dalakas, Marinos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119813/
https://www.ncbi.nlm.nih.gov/pubmed/37059468
http://dx.doi.org/10.1212/NXI.0000000000200109