Vaccination with recombinant Lactococcus lactis expressing HA1-IgY Fc fusion protein provides protective mucosal immunity against H9N2 avian influenza virus in chickens

BACKGROUND: H9N2 virus is mainly transmitted through the respiratory mucosal pathway, so mucosal immunity is considered to play a good role in controlling avian influenza infection. It is commonly accepted that no adequate mucosal immunity is achieved by inactivated vaccines, which was widely used t...

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Detalles Bibliográficos
Autores principales: Zhang, Ruihua, Xu, Tong, Li, Ziping, Li, Longfei, Li, Chunhong, Li, Xinrui, Wang, Zhiyue, Wang, Shaohua, Wang, Xuejing, Zhang, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119832/
https://www.ncbi.nlm.nih.gov/pubmed/37085816
http://dx.doi.org/10.1186/s12985-023-02044-9

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