Cargando…
Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV)
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the feed additive containing endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 36...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119908/ https://www.ncbi.nlm.nih.gov/pubmed/37089170 http://dx.doi.org/10.2903/j.efsa.2023.7954 |
_version_ | 1785029089151680512 |
---|---|
author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Anguita, Montserrat Galobart, Jaume Tarrés‐Call, Jordi Pettenati, Elisa Ortuño, Jordi |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Anguita, Montserrat Galobart, Jaume Tarrés‐Call, Jordi Pettenati, Elisa Ortuño, Jordi |
collection | PubMed |
description | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the feed additive containing endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym® C). The product is authorised as a zootechnical additive (functional group: digestibility enhancers) for use in chickens for fattening, minor poultry species for fattening and weaned piglets. This scientific opinion concerns the request for the renewal of the authorisation for the use in those species/categories, and the extension of use to chickens reared for laying, turkeys reared for breeding, minor poultry species reared for laying or breeding, ornamental birds and suckling piglets. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the Panel to reconsider previous conclusions that the additive is safe for the target species, the consumers, and the environment under the authorised conditions of use. This conclusion also applies to the target species for which a request for an extension of use is made. The additive is considered not a skin corrosive or eye irritant, but it should be considered a skin sensitiser. The Panel cannot conclude on the potential of the additive to be a skin irritant. Due to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The Panel considers that the additive has the potential to be efficacious at 500 CU/kg complete feed in all poultry for fattening, reared for laying or breeding, and ornamental birds, and at 350 CU/kg complete feed in piglets (weaned and suckling, for the period in which solid feed is given). |
format | Online Article Text |
id | pubmed-10119908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101199082023-04-22 Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Anguita, Montserrat Galobart, Jaume Tarrés‐Call, Jordi Pettenati, Elisa Ortuño, Jordi EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the feed additive containing endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym® C). The product is authorised as a zootechnical additive (functional group: digestibility enhancers) for use in chickens for fattening, minor poultry species for fattening and weaned piglets. This scientific opinion concerns the request for the renewal of the authorisation for the use in those species/categories, and the extension of use to chickens reared for laying, turkeys reared for breeding, minor poultry species reared for laying or breeding, ornamental birds and suckling piglets. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the Panel to reconsider previous conclusions that the additive is safe for the target species, the consumers, and the environment under the authorised conditions of use. This conclusion also applies to the target species for which a request for an extension of use is made. The additive is considered not a skin corrosive or eye irritant, but it should be considered a skin sensitiser. The Panel cannot conclude on the potential of the additive to be a skin irritant. Due to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The Panel considers that the additive has the potential to be efficacious at 500 CU/kg complete feed in all poultry for fattening, reared for laying or breeding, and ornamental birds, and at 350 CU/kg complete feed in piglets (weaned and suckling, for the period in which solid feed is given). John Wiley and Sons Inc. 2023-04-21 /pmc/articles/PMC10119908/ /pubmed/37089170 http://dx.doi.org/10.2903/j.efsa.2023.7954 Text en © 2023 European Food Safety Authority. EFSA Journal published by Wiley‐VCH GmbH on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Anguita, Montserrat Galobart, Jaume Tarrés‐Call, Jordi Pettenati, Elisa Ortuño, Jordi Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title | Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title_full | Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title_fullStr | Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title_full_unstemmed | Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title_short | Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym C) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (Huvepharma NV) |
title_sort | safety and efficacy of a feed additive consisting of endo‐1,4‐β‐glucanase produced by trichoderma citrinoviride imi 360748 (hostazym c) for use in all poultry species for fattening and reared for laying/breeding, ornamental birds and piglets (weaned and suckling) (huvepharma nv) |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119908/ https://www.ncbi.nlm.nih.gov/pubmed/37089170 http://dx.doi.org/10.2903/j.efsa.2023.7954 |
work_keys_str_mv | AT safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT bampidisvasileios safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT azimontigiovanna safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT bastosmariadelourdes safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT christensenhenrik safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT dusemundbirgit safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT durjavamojca safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT koubamaryline safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT lopezalonsomarta safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT lopezpuentesecundino safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT marconfrancesca safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT mayobaltasar safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT pechovaalena safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT petkovamariana safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT ramosfernando safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT sanzyolanda safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT villarobertoedoardo safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT woutersenruud safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT anguitamontserrat safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT galobartjaume safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT tarrescalljordi safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT pettenatielisa safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv AT ortunojordi safetyandefficacyofafeedadditiveconsistingofendo14bglucanaseproducedbytrichodermacitrinovirideimi360748hostazymcforuseinallpoultryspeciesforfatteningandrearedforlayingbreedingornamentalbirdsandpigletsweanedandsucklinghuvepharmanv |