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On the Origins of Enzymes: Phosphate-Binding Polypeptides Mediate Phosphoryl Transfer to Synthesize Adenosine Triphosphate

[Image: see text] Reactions involving the transfer of a phosphoryl (−PO(3)(2–)) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the phosphate-binding loop (P-loop) nucleoside triphosphatase (NTPase) superfamily. Due to the...

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Detalles Bibliográficos
Autores principales: Vyas, Pratik, Malitsky, Sergey, Itkin, Maxim, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119929/
https://www.ncbi.nlm.nih.gov/pubmed/36951643
http://dx.doi.org/10.1021/jacs.2c08636