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Dual Molecules Targeting 5-HT(6) and GABA-A Receptors as a New Approach to Combat Depression Associated with Neuroinflammation

[Image: see text] While monoaminergic deficits are evident in all depressed patients, nonresponders are characterized by impaired GABA-ergic signaling and the simultaneous presence of the inflammatory component. Pharmacological agents able to curb pathological immune responses and modulate ineffecti...

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Detalles Bibliográficos
Autores principales: Marcinkowska, Monika, Mordyl, Barbara, Siwek, Agata, Głuch-Lutwin, Monika, Karcz, Tadeusz, Gawalska, Alicja, Sapa, Michał, Bucki, Adam, Szafrańska, Katarzyna, Pomierny, Bartosz, Pytka, Karolina, Kotańska, Magdalena, Mika, Kamil, Kolaczkowski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119930/
https://www.ncbi.nlm.nih.gov/pubmed/37014731
http://dx.doi.org/10.1021/acschemneuro.3c00033