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Dual Molecules Targeting 5-HT(6) and GABA-A Receptors as a New Approach to Combat Depression Associated with Neuroinflammation
[Image: see text] While monoaminergic deficits are evident in all depressed patients, nonresponders are characterized by impaired GABA-ergic signaling and the simultaneous presence of the inflammatory component. Pharmacological agents able to curb pathological immune responses and modulate ineffecti...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119930/ https://www.ncbi.nlm.nih.gov/pubmed/37014731 http://dx.doi.org/10.1021/acschemneuro.3c00033 |