AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production

[Image: see text] The site-directed chemical conjugation of antibodies remains an area of great interest and active efforts within the antibody–drug conjugate (ADC) community. We previously reported a unique site modification using a class of immunoglobulin-G (IgG) Fc-affinity reagents to establish...

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Detalles Bibliográficos
Autores principales: Fujii, Tomohiro, Matsuda, Yutaka, Seki, Takuya, Shikida, Natsuki, Iwai, Yusuke, Ooba, Yuri, Takahashi, Kazutoshi, Isokawa, Muneki, Kawaguchi, Sayaka, Hatada, Noriko, Watanabe, Tomohiro, Takasugi, Rika, Nakayama, Akira, Shimbo, Kazutaka, Mendelsohn, Brian A., Okuzumi, Tatsuya, Yamada, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119932/
https://www.ncbi.nlm.nih.gov/pubmed/36894324
http://dx.doi.org/10.1021/acs.bioconjchem.3c00040

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