JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology

[Image: see text] c-Jun N-terminal kinase 3 (JNK3) is suggested to play a key role in neurodegenerative disorders, especially in Alzheimer’s disease (AD). However, it remains unclear whether JNK or amyloid β (Aβ) appears first in the disease onset. Postmortem brain tissues from four dementia subtype...

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Detalles Bibliográficos
Autores principales: Solas, Maite, Vela, Silvia, Smerdou, Cristian, Martisova, Eva, Martínez-Valbuena, Iván, Luquin, María-Rosario, Ramírez, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119940/
https://www.ncbi.nlm.nih.gov/pubmed/36976903
http://dx.doi.org/10.1021/acschemneuro.3c00093

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