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Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress
The General Amino Acid Control is a conserved response to amino acid starvation involving activation of protein kinase Gcn2, which phosphorylates eukaryotic initiation factor 2 (eIF2α) with attendant inhibition of global protein synthesis and increased translation of yeast transcriptional activator...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120022/ https://www.ncbi.nlm.nih.gov/pubmed/37043534 http://dx.doi.org/10.1073/pnas.2300521120 |