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Electroanalytical Overview: The Determination of Levodopa (L-DOPA)

[Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but ar...

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Autores principales: Crapnell, Robert D., Banks, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120037/
https://www.ncbi.nlm.nih.gov/pubmed/37090256
http://dx.doi.org/10.1021/acsmeasuresciau.2c00071
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author Crapnell, Robert D.
Banks, Craig E.
author_facet Crapnell, Robert D.
Banks, Craig E.
author_sort Crapnell, Robert D.
collection PubMed
description [Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but are not always available in clinical settings and traditional research laboratories, and they also have slow result delivery times and high costs. The use of electroanalytical sensing overcomes these problems providing a highly sensitivity, low-cost, and readily portable solution. Consequently, we overview the electroanalytical determination of L-DOPA reported throughout the literature summarizing the endeavors toward sensing L-DOPA, and we offer insights into future research opportunities.
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spelling pubmed-101200372023-04-22 Electroanalytical Overview: The Determination of Levodopa (L-DOPA) Crapnell, Robert D. Banks, Craig E. ACS Meas Sci Au [Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but are not always available in clinical settings and traditional research laboratories, and they also have slow result delivery times and high costs. The use of electroanalytical sensing overcomes these problems providing a highly sensitivity, low-cost, and readily portable solution. Consequently, we overview the electroanalytical determination of L-DOPA reported throughout the literature summarizing the endeavors toward sensing L-DOPA, and we offer insights into future research opportunities. American Chemical Society 2023-02-03 /pmc/articles/PMC10120037/ /pubmed/37090256 http://dx.doi.org/10.1021/acsmeasuresciau.2c00071 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Crapnell, Robert D.
Banks, Craig E.
Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title_full Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title_fullStr Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title_full_unstemmed Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title_short Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
title_sort electroanalytical overview: the determination of levodopa (l-dopa)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120037/
https://www.ncbi.nlm.nih.gov/pubmed/37090256
http://dx.doi.org/10.1021/acsmeasuresciau.2c00071
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