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Electroanalytical Overview: The Determination of Levodopa (L-DOPA)
[Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but ar...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120037/ https://www.ncbi.nlm.nih.gov/pubmed/37090256 http://dx.doi.org/10.1021/acsmeasuresciau.2c00071 |
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author | Crapnell, Robert D. Banks, Craig E. |
author_facet | Crapnell, Robert D. Banks, Craig E. |
author_sort | Crapnell, Robert D. |
collection | PubMed |
description | [Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but are not always available in clinical settings and traditional research laboratories, and they also have slow result delivery times and high costs. The use of electroanalytical sensing overcomes these problems providing a highly sensitivity, low-cost, and readily portable solution. Consequently, we overview the electroanalytical determination of L-DOPA reported throughout the literature summarizing the endeavors toward sensing L-DOPA, and we offer insights into future research opportunities. |
format | Online Article Text |
id | pubmed-10120037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-101200372023-04-22 Electroanalytical Overview: The Determination of Levodopa (L-DOPA) Crapnell, Robert D. Banks, Craig E. ACS Meas Sci Au [Image: see text] L-DOPA (levodopa) is a therapeutic agent which is the most effective medication for treating Parkinson’s disease, but it needs dose optimization, and therefore its analytical determination is required. Laboratory analytical instruments can be routinely used to measure L-DOPA but are not always available in clinical settings and traditional research laboratories, and they also have slow result delivery times and high costs. The use of electroanalytical sensing overcomes these problems providing a highly sensitivity, low-cost, and readily portable solution. Consequently, we overview the electroanalytical determination of L-DOPA reported throughout the literature summarizing the endeavors toward sensing L-DOPA, and we offer insights into future research opportunities. American Chemical Society 2023-02-03 /pmc/articles/PMC10120037/ /pubmed/37090256 http://dx.doi.org/10.1021/acsmeasuresciau.2c00071 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Crapnell, Robert D. Banks, Craig E. Electroanalytical Overview: The Determination of Levodopa (L-DOPA) |
title | Electroanalytical
Overview: The Determination of Levodopa
(L-DOPA) |
title_full | Electroanalytical
Overview: The Determination of Levodopa
(L-DOPA) |
title_fullStr | Electroanalytical
Overview: The Determination of Levodopa
(L-DOPA) |
title_full_unstemmed | Electroanalytical
Overview: The Determination of Levodopa
(L-DOPA) |
title_short | Electroanalytical
Overview: The Determination of Levodopa
(L-DOPA) |
title_sort | electroanalytical
overview: the determination of levodopa
(l-dopa) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120037/ https://www.ncbi.nlm.nih.gov/pubmed/37090256 http://dx.doi.org/10.1021/acsmeasuresciau.2c00071 |
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