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The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells

BACKGROUND: Both IGF-1R/PI3K/AKT/mTOR and Hippo pathways are crucial for breast cancer stem cells (BCSCs). However, their interplay remains unclear. METHODS: Four triple negative breast cancer cell lines derived from CSC of two patient-derived xenografts (PDXs), AS-B145, AS-B145-1R, AS-B244, and AS-...

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Detalles Bibliográficos
Autores principales:	Chan, Yu-Tzu, Lin, Ruey-Jen, Wang, Ya-Hui, Hung, Tsai-Hsien, Huang, Yenlin, Yu, John, Yu, Jyh-Cherng, Yu, Alice L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120239/ https://www.ncbi.nlm.nih.gov/pubmed/37081542 http://dx.doi.org/10.1186/s12964-023-01088-2

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