Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) affects young women and is the most aggressive subtype of breast cancer (BC). TNBCs disproportionally affect women of African-American (AA) descent compared to other ethnicities. We have identified DNA repair gene RAD51 as a poor prognosis marker in T...

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Detalles Bibliográficos
Autores principales: Mani, Chinnadurai, Acharya, Ganesh, Saamarthy, Karunakar, Ochola, Damieanus, Mereddy, Srinidhi, Pruitt, Kevin, Manne, Upender, Palle, Komaraiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120249/
https://www.ncbi.nlm.nih.gov/pubmed/37081516
http://dx.doi.org/10.1186/s13058-023-01615-6

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