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High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial

Background Extubation failure is associated with increased morbidity and poor outcomes. This study aimed to ascertain the effectiveness of a high-flow nasal cannula (HFNC) as a weaning method compared to conventional weaning. Methodology A total of 60 mechanically ventilated patients, aged 18-65 yea...

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Autores principales: Arora, Gauri, Arshad, Zia, Prakash, Ravi, Sharma, Mudita, Singh, Gyan Prakash, Kohli, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120274/
https://www.ncbi.nlm.nih.gov/pubmed/37090360
http://dx.doi.org/10.7759/cureus.36511
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author Arora, Gauri
Arshad, Zia
Prakash, Ravi
Sharma, Mudita
Singh, Gyan Prakash
Kohli, Monica
author_facet Arora, Gauri
Arshad, Zia
Prakash, Ravi
Sharma, Mudita
Singh, Gyan Prakash
Kohli, Monica
author_sort Arora, Gauri
collection PubMed
description Background Extubation failure is associated with increased morbidity and poor outcomes. This study aimed to ascertain the effectiveness of a high-flow nasal cannula (HFNC) as a weaning method compared to conventional weaning. Methodology A total of 60 mechanically ventilated patients, aged 18-65 years, who were ventilated for 48 hours and whose underlying pathology had either resolved or was improving, were enrolled in this study. They were randomized in a 1:1 ratio to participate in the HFNC weaning method or receive conventional weaning. Patients in Group A were extubated and oxygen was provided via HFNC. Group B patients were given a spontaneous breathing trial (SBT) per the standard protocol and extubated after a successful SBT. Results Weaning failure was found in five patients and was higher in the conventional group (three patients in the conventional group and two patients in the HFNC group). The duration of stay of patients in intensive care units was significantly higher in the conventional group than in the HFNC group. Conclusions HFNC is a better alternative to conventional weaning through SBT.
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spelling pubmed-101202742023-04-22 High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial Arora, Gauri Arshad, Zia Prakash, Ravi Sharma, Mudita Singh, Gyan Prakash Kohli, Monica Cureus Anesthesiology Background Extubation failure is associated with increased morbidity and poor outcomes. This study aimed to ascertain the effectiveness of a high-flow nasal cannula (HFNC) as a weaning method compared to conventional weaning. Methodology A total of 60 mechanically ventilated patients, aged 18-65 years, who were ventilated for 48 hours and whose underlying pathology had either resolved or was improving, were enrolled in this study. They were randomized in a 1:1 ratio to participate in the HFNC weaning method or receive conventional weaning. Patients in Group A were extubated and oxygen was provided via HFNC. Group B patients were given a spontaneous breathing trial (SBT) per the standard protocol and extubated after a successful SBT. Results Weaning failure was found in five patients and was higher in the conventional group (three patients in the conventional group and two patients in the HFNC group). The duration of stay of patients in intensive care units was significantly higher in the conventional group than in the HFNC group. Conclusions HFNC is a better alternative to conventional weaning through SBT. Cureus 2023-03-22 /pmc/articles/PMC10120274/ /pubmed/37090360 http://dx.doi.org/10.7759/cureus.36511 Text en Copyright © 2023, Arora et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Arora, Gauri
Arshad, Zia
Prakash, Ravi
Sharma, Mudita
Singh, Gyan Prakash
Kohli, Monica
High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title_full High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title_fullStr High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title_full_unstemmed High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title_short High-Flow Nasal Cannula as an Alternate Weaning Strategy: A Randomized Controlled Trial
title_sort high-flow nasal cannula as an alternate weaning strategy: a randomized controlled trial
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120274/
https://www.ncbi.nlm.nih.gov/pubmed/37090360
http://dx.doi.org/10.7759/cureus.36511
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