Hexokinases in cancer and other pathologies

Glucose metabolism is indispensable for cell growth and survival. Hexokinases play pivotal roles in glucose metabolism through canonical functions of hexokinases as well as in immune response, cell stemness, autophagy, and other cellular activities through noncanonical functions. The aberrant regula...

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Detalles Bibliográficos
Autores principales: Guo, Dong, Meng, Ying, Jiang, Xiaoming, Lu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120283/
https://www.ncbi.nlm.nih.gov/pubmed/37192912
http://dx.doi.org/10.1016/j.cellin.2023.100077
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author Guo, Dong
Meng, Ying
Jiang, Xiaoming
Lu, Zhimin
author_facet Guo, Dong
Meng, Ying
Jiang, Xiaoming
Lu, Zhimin
author_sort Guo, Dong
collection PubMed
description Glucose metabolism is indispensable for cell growth and survival. Hexokinases play pivotal roles in glucose metabolism through canonical functions of hexokinases as well as in immune response, cell stemness, autophagy, and other cellular activities through noncanonical functions. The aberrant regulation of hexokinases contributes to the development and progression of pathologies, including cancer and immune diseases.
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spelling pubmed-101202832023-05-15 Hexokinases in cancer and other pathologies Guo, Dong Meng, Ying Jiang, Xiaoming Lu, Zhimin Cell Insight Review Glucose metabolism is indispensable for cell growth and survival. Hexokinases play pivotal roles in glucose metabolism through canonical functions of hexokinases as well as in immune response, cell stemness, autophagy, and other cellular activities through noncanonical functions. The aberrant regulation of hexokinases contributes to the development and progression of pathologies, including cancer and immune diseases. Elsevier 2023-01-03 /pmc/articles/PMC10120283/ /pubmed/37192912 http://dx.doi.org/10.1016/j.cellin.2023.100077 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Guo, Dong
Meng, Ying
Jiang, Xiaoming
Lu, Zhimin
Hexokinases in cancer and other pathologies
title Hexokinases in cancer and other pathologies
title_full Hexokinases in cancer and other pathologies
title_fullStr Hexokinases in cancer and other pathologies
title_full_unstemmed Hexokinases in cancer and other pathologies
title_short Hexokinases in cancer and other pathologies
title_sort hexokinases in cancer and other pathologies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120283/
https://www.ncbi.nlm.nih.gov/pubmed/37192912
http://dx.doi.org/10.1016/j.cellin.2023.100077
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AT mengying hexokinasesincancerandotherpathologies
AT jiangxiaoming hexokinasesincancerandotherpathologies
AT luzhimin hexokinasesincancerandotherpathologies

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