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Deciphering aging at three-dimensional genomic resolution
Aging is characterized by progressive functional declines at the organismal, organic, and cellular levels and increased susceptibility to aging-related diseases. Epigenetic alteration is a hallmark of aging, senescent cells show epigenomic changes at multiple scales, such as 3D genome reorganization...
Autores principales: | Liu, Zunpeng, Belmonte, Juan Carlos Izpisua, Zhang, Weiqi, Qu, Jing, Liu, Guang-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120299/ https://www.ncbi.nlm.nih.gov/pubmed/37193050 http://dx.doi.org/10.1016/j.cellin.2022.100034 |
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