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Deciphering aging at three-dimensional genomic resolution

Aging is characterized by progressive functional declines at the organismal, organic, and cellular levels and increased susceptibility to aging-related diseases. Epigenetic alteration is a hallmark of aging, senescent cells show epigenomic changes at multiple scales, such as 3D genome reorganization...

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Detalles Bibliográficos
Autores principales: Liu, Zunpeng, Belmonte, Juan Carlos Izpisua, Zhang, Weiqi, Qu, Jing, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120299/
https://www.ncbi.nlm.nih.gov/pubmed/37193050
http://dx.doi.org/10.1016/j.cellin.2022.100034

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