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Structural basis of the TCR-pHLA complex provides insights into the unconventional recognition of CDR3β in TCR cross-reactivity and alloreactivity

Evidence shows that some class I human leucocyte antigen (HLA) alleles are related to durable HIV controls. The T18A TCR, which has the alloreactivity between HLA-B∗42:01 and HLA-B∗81:01 and the cross-reactivity with different antigen mutants, can sustain long-term HIV controls. Here the structural...

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Detalles Bibliográficos
Autores principales:	San, Dan, Lei, Jun, Liu, Yang, Jing, Baowei, Ye, Xiang, Wei, Pengcheng, Paek, Chonil, Yang, Yi, Zhou, Jin, Chen, Peng, Wang, Hongjian, Chen, Yongshun, Yin, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120306/ https://www.ncbi.nlm.nih.gov/pubmed/37192909 http://dx.doi.org/10.1016/j.cellin.2022.100076

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