Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity

Epidermal growth factor receptor (EGFR) plays critical roles in cell proliferation and tumorigenesis. Autophagy has emerged as a potential mechanism involved in the acquired resistance to anti-EGFR treatments, however, the molecular mechanisms has not been fully addressed. In this study, we identifi...

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Detalles Bibliográficos
Autores principales: Zhou, Cefan, Dong, Xueying, Wang, Ming, Qian, Xuehong, Hu, Miao, Liang, Kai, Liang, Yanyan, Zhang, Rui, Huang, Yuan, Lyu, Hao, Xiao, Shuai, Tang, Yongfei, Ali, Declan William, Michalak, Marek, Chen, Xing-Zhen, Tang, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120315/
https://www.ncbi.nlm.nih.gov/pubmed/37192859
http://dx.doi.org/10.1016/j.cellin.2022.100045

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