USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network

Inflammatory bowel disease (IBD) is closely associated with dysregulation of genetic factors and microbial environment. Here, we report a susceptible role of ubiquitin-specific protease 2 (USP2) in experimental colitis and bacterial infections. USP2 is upregulated in the inflamed mucosa of IBD patie...

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Detalles Bibliográficos
Autores principales: An, Ran, Wang, Peng, Guo, Hao, Liuyu, Tianzi, Zhong, Bo, Zhang, Zhi-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120320/
https://www.ncbi.nlm.nih.gov/pubmed/37192862
http://dx.doi.org/10.1016/j.cellin.2022.100047

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