Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Candida glabrata activity

A series of 21 novel compounds containing a thiosemicarbazone moiety were designed and synthesised based on hit compound 1 from our in-house compound library screening. Most compounds showed potent antifungal activity in vitro against seven common pathogenic fungi. Notably, all compounds showed high...

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Detalles Bibliográficos
Autores principales: Li, Xianru, Li, Liping, Zhang, Haonan, Chi, Xiaochen, Jiang, Yuanying, Ni, Tingjunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120463/
https://www.ncbi.nlm.nih.gov/pubmed/37080774
http://dx.doi.org/10.1080/14756366.2023.2202362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120463/
https://www.ncbi.nlm.nih.gov/pubmed/37080774
http://dx.doi.org/10.1080/14756366.2023.2202362

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