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Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Candida glabrata activity
A series of 21 novel compounds containing a thiosemicarbazone moiety were designed and synthesised based on hit compound 1 from our in-house compound library screening. Most compounds showed potent antifungal activity in vitro against seven common pathogenic fungi. Notably, all compounds showed high...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120463/ https://www.ncbi.nlm.nih.gov/pubmed/37080774 http://dx.doi.org/10.1080/14756366.2023.2202362 |