Iron overload induces islet β cell ferroptosis by activating ASK1/P-P38/CHOP signaling pathway

BACKGROUND: Recent studies have shown that the accumulation of free iron and lipid peroxides will trigger a new form of cell death—ferroptosis. This form of cell death is associated with a variety of diseases, including type 2 diabetes. We hypothesize that iron overload may play a role in driving gl...

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Detalles Bibliográficos
Autores principales: Deng, Ling, Mo, Man-Qiu, Zhong, Jinling, Li, Zhengming, Li, Guoqiao, Liang, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Diabetes and Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120586/
https://www.ncbi.nlm.nih.gov/pubmed/37090106
http://dx.doi.org/10.7717/peerj.15206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120586/
https://www.ncbi.nlm.nih.gov/pubmed/37090106
http://dx.doi.org/10.7717/peerj.15206

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