Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseased tissue gene expression profiles in silico

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Preclinical models like cancer cell lines and patient-derived xenografts (PDXs) are vital for studying disease mechanisms and evaluating treatment options. It is essential that they accurately recapitulate the disease state of interest to generate results that will translate in the clinic. Prior stu...

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Detalles Bibliográficos
Autores principales: Williams, Avery S., Wilk, Elizabeth J., Fisher, Jennifer L., Lasseigne, Brittany N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120639/
https://www.ncbi.nlm.nih.gov/pubmed/37090499
http://dx.doi.org/10.1101/2023.04.11.536431
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