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RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks in human cells
Replication gaps can arise as a consequence of perturbed DNA replication and their accumulation might undermine the stability of the genome. Loss of RAD52, a protein involved in the regulation of fork reversal, promotes accumulation of parental ssDNA gaps during replication perturbation. Here, we de...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120653/ https://www.ncbi.nlm.nih.gov/pubmed/37090680 http://dx.doi.org/10.1101/2023.04.12.536536 |