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Developing an evolutionary baseline model for humans: jointly inferring purifying selection with population history

Building evolutionarily appropriate baseline models for natural populations is not only important for answering fundamental questions in population genetics – including quantifying the relative contributions of adaptive vs. non-adaptive processes – but it is also essential for identifying candidate...

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Detalles Bibliográficos
Autores principales: Johri, Parul, Pfeifer, Susanne P., Jensen, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120674/
https://www.ncbi.nlm.nih.gov/pubmed/37090533
http://dx.doi.org/10.1101/2023.04.11.536488