Highly specific σ(2)R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response

The Sigma 2 receptor (σ(2)R) was described pharmacologically more than three decades ago, but its molecular identity remained obscure until recently when it was identified as transmembrane protein 97 (TMEM97). We and others have shown that σ(2)R/TMEM97 ligands alleviate mechanical hypersensitivity i...

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Detalles Bibliográficos
Autores principales: Yousuf, Muhammad Saad, Sahn, James J., Yang, Hongfen, David, Eric T., Shiers, Stephanie, Moreno, Marisol Mancilla, Iketem, Jonathan, Royer, Danielle M., Garcia, Chelsea D., Zhang, Jennifer, Hong, Veronica M., Mian, Subhaan M., Ahmad, Ayesha, Kolber, Benedict J., Liebl, Daniel J, Martin, Stephen F., Price, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120691/
https://www.ncbi.nlm.nih.gov/pubmed/37090527
http://dx.doi.org/10.1101/2023.04.11.536439

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