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LinRace: single cell lineage reconstruction using paired lineage barcode and gene expression data

Understanding how single cells divide and differentiate into different cell types in developed organs is one of the major tasks of developmental and stem cell biology. Recently, lineage tracing technology using CRISPR/Cas9 genome editing has enabled simultaneous readouts of gene expressions and line...

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Detalles Bibliográficos
Autores principales: Pan, Xinhai, Li, Hechen, Putta, Pranav, Zhang, Xiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120693/
https://www.ncbi.nlm.nih.gov/pubmed/37090498
http://dx.doi.org/10.1101/2023.04.12.536601