Cargando…

Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance

Extracellular matrix (ECM) protein expression/deposition within and stiffening of the breast cancer microenvironment facilitates disease progression and correlates with poor patient survival. However, the mechanisms by which ECM components control tumorigenic behaviors and responses to therapeutic i...

Descripción completa

Detalles Bibliográficos
Autores principales: Geller, Cameron, Maddela, Joanna, Tuplano, Ranel, Runa, Farhana, Adamian, Yvess, Güth, Robert, Ortiz Soto, Gabriela, Tomaneng, Luke, Cantor, Joseph, Kelber, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120696/
https://www.ncbi.nlm.nih.gov/pubmed/37090582
http://dx.doi.org/10.1101/2023.04.13.536765