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HIV reservoirs are dominated by genetically younger and clonally enriched proviruses

In order to cure HIV, we need to better understand the within-host evolutionary origins of the small reservoir of genome-intact proviruses that persists within infected cells during antiretroviral therapy (ART). Most prior studies on reservoir evolutionary dynamics however did not discriminate genom...

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Detalles Bibliográficos
Autores principales:	Kinloch, Natalie N., Shahid, Aniqa, Dong, Winnie, Kirkby, Don, Jones, Bradley R., Beelen, Charlotte J., MacMillan, Daniel, Lee, Guinevere Q., Mota, Talia M., Sudderuddin, Hanwei, Barad, Evan, Harris, Marianne, Brumme, Chanson J., Jones, R. Brad, Brockman, Mark A., Joy, Jeffrey B., Brumme, Zabrina L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120704/ https://www.ncbi.nlm.nih.gov/pubmed/37090500 http://dx.doi.org/10.1101/2023.04.12.536611

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