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Widespread CRISPR repeat-like RNA regulatory elements in CRISPR-Cas systems

CRISPR-cas loci typically contain CRISPR arrays with unique spacers separating direct repeats. Spacers along with portions of adjacent repeats are transcribed and processed into CRISPR(cr) RNAs that target complementary sequences (protospacers) in mobile genetic elements, resulting in cleavage of th...

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Detalles Bibliográficos
Autores principales: Shmakov, Sergey A., Barth, Zachary K., Makarova, Kira S., Wolf, Yuri I., Brover, Vyacheslav, Peters, Joseph E., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120712/
https://www.ncbi.nlm.nih.gov/pubmed/37090614
http://dx.doi.org/10.1101/2023.03.03.530964

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