Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs

Hybridization of short nucleic acid segments (<4 nucleotides) to single-strand templates occurs as a critical intermediate in processes such as non-enzymatic nucleic acid replication and toehold-mediated strand displacement. These templates often contain adjacent duplex segments that stabilize ba...

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Detalles Bibliográficos
Autores principales: Ashwood, Brennan, Jones, Michael S., Radakovic, Aleksandar, Khanna, Smayan, Lee, Yumin, Sachleben, Joseph R., Szostak, Jack W., Ferguson, Andrew L., Tokmakoff, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120721/
https://www.ncbi.nlm.nih.gov/pubmed/37090657
http://dx.doi.org/10.1101/2023.04.10.536266

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