Enantio- and Diastereoenriched Enzymatic Synthesis of 1,2,3-Polysubstituted Cyclopropanes from (Z/E)-Trisubstituted Enol Acetates

In nature and synthetic chemistry, stereoselective [2+1] cyclopropanation is the most prevalent strategy for the synthesis of chiral cyclopropanes, a class of key pharmacophores in pharmaceuticals and bioactive natural products. One of the most extensively studied reactions in the organic chemist’s...

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Detalles Bibliográficos
Autores principales: Mao, Runze, Wackelin, Daniel J., Jamieson, Cooper S., Rogge, Torben, Gao, Shilong, Das, Anuvab, Taylor, Doris Mia, Houk, K. N., Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120758/
https://www.ncbi.nlm.nih.gov/pubmed/37090661
http://dx.doi.org/10.21203/rs.3.rs-2802333/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120758/
https://www.ncbi.nlm.nih.gov/pubmed/37090661
http://dx.doi.org/10.21203/rs.3.rs-2802333/v1

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