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Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis

Tuberculosis (TB) is the most common cause of death in people living with HIV. BCG delivered intradermally (ID) is the only licensed vaccine to prevent TB. However, it offers little protection from pulmonary TB in adults. Intravenous (IV) BCG, but not ID BCG, confers striking protection against Myco...

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Detalles Bibliográficos
Autores principales: Larson, Erica C., Ellis-Connell, Amy L., Rodgers, Mark A., Gubernat, Abigail K., Gleim, Janelle L., Moriarty, Ryan V., Balgeman, Alexis J., Ameel, Cassaundra L., Jauro, Solomon, Tomko, Jaime A., Kracinovsky, Kara B., Maiello, Pauline, Borish, H. Jake, White, Alexander G., Klein, Edwin, Bucsan, Allison N., Darrah, Patricia A., Seder, Robert A., Roederer, Mario, Lin, Philana Ling, Flynn, JoAnne L., O’Connor, Shelby L., Scanga, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120779/
https://www.ncbi.nlm.nih.gov/pubmed/37090620
http://dx.doi.org/10.21203/rs.3.rs-2802306/v1