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Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia

Background: Androgenetic alopecia (AGA) is a common cause of hair loss in men with limited treatment options. Platelet-rich plasma (PRP) therapy is one of the newer treatment modalities in the management of AGA with promising results. Aim: The aim is to assess the efficacy of PRP in males with AGA a...

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Autores principales: Manickam, Navakumar, Mathapati, Prashant, Somasundaram, Keerthana, Gopalan, Kannan, Ganga Vellaisamy, Seethalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120877/
https://www.ncbi.nlm.nih.gov/pubmed/37090365
http://dx.doi.org/10.7759/cureus.36531
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author Manickam, Navakumar
Mathapati, Prashant
Somasundaram, Keerthana
Gopalan, Kannan
Ganga Vellaisamy, Seethalakshmi
author_facet Manickam, Navakumar
Mathapati, Prashant
Somasundaram, Keerthana
Gopalan, Kannan
Ganga Vellaisamy, Seethalakshmi
author_sort Manickam, Navakumar
collection PubMed
description Background: Androgenetic alopecia (AGA) is a common cause of hair loss in men with limited treatment options. Platelet-rich plasma (PRP) therapy is one of the newer treatment modalities in the management of AGA with promising results. Aim: The aim is to assess the efficacy of PRP in males with AGA and to study any adverse events associated with the procedure. Methods: A total of 30 patients participated in the study, and they were administered PRP injections every three weeks for four sessions. An evaluator’s visual assessment of improvement based on digital photographs was done at three, six, and nine weeks and then at the end of the fourth month. The patient’s perception of improvement was evaluated on a 7-point scale at the baseline and at the end of the fourth month. Results: Of the 30 participants, 27 completed all four sessions. Mild improvement was seen in 13 (48.1%) patients, moderate improvement was seen in five (18.5%) patients, and excellent improvement was seen in one (3.7%) patient. Six (22.2%) patients had involvement in the vertex region of the scalp; of them, three (50%) had moderate improvement, one (16.7%) had excellent improvement, and two (33.3%) had mild improvement. Twenty-one (77.8%) patients had involvement in the fronto-temporal region of the scalp, of which nine (42.9%) had mild improvement, and five (23.8%) had moderate improvement. Conclusion: PRP treatment alone appeared to be a simple, cost-effective treatment for AGA with good results.
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spelling pubmed-101208772023-04-22 Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia Manickam, Navakumar Mathapati, Prashant Somasundaram, Keerthana Gopalan, Kannan Ganga Vellaisamy, Seethalakshmi Cureus Dermatology Background: Androgenetic alopecia (AGA) is a common cause of hair loss in men with limited treatment options. Platelet-rich plasma (PRP) therapy is one of the newer treatment modalities in the management of AGA with promising results. Aim: The aim is to assess the efficacy of PRP in males with AGA and to study any adverse events associated with the procedure. Methods: A total of 30 patients participated in the study, and they were administered PRP injections every three weeks for four sessions. An evaluator’s visual assessment of improvement based on digital photographs was done at three, six, and nine weeks and then at the end of the fourth month. The patient’s perception of improvement was evaluated on a 7-point scale at the baseline and at the end of the fourth month. Results: Of the 30 participants, 27 completed all four sessions. Mild improvement was seen in 13 (48.1%) patients, moderate improvement was seen in five (18.5%) patients, and excellent improvement was seen in one (3.7%) patient. Six (22.2%) patients had involvement in the vertex region of the scalp; of them, three (50%) had moderate improvement, one (16.7%) had excellent improvement, and two (33.3%) had mild improvement. Twenty-one (77.8%) patients had involvement in the fronto-temporal region of the scalp, of which nine (42.9%) had mild improvement, and five (23.8%) had moderate improvement. Conclusion: PRP treatment alone appeared to be a simple, cost-effective treatment for AGA with good results. Cureus 2023-03-22 /pmc/articles/PMC10120877/ /pubmed/37090365 http://dx.doi.org/10.7759/cureus.36531 Text en Copyright © 2023, Manickam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Manickam, Navakumar
Mathapati, Prashant
Somasundaram, Keerthana
Gopalan, Kannan
Ganga Vellaisamy, Seethalakshmi
Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title_full Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title_fullStr Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title_full_unstemmed Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title_short Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia
title_sort efficacy of platelet-rich plasma in males with androgenetic alopecia
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120877/
https://www.ncbi.nlm.nih.gov/pubmed/37090365
http://dx.doi.org/10.7759/cureus.36531
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