A Rare Case of Paxlovid-Induced Pancreatitis

Acute pancreatitis can result secondary to an inflammatory cascade due to an insult to the pancreatic parenchyma, whether it be from infections, medications, etc. We present a case of a 37-year-old male with acute pancreatitis after being started on Paxlovid, a combination drug containing Nirmatrelv...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaidi, Syed Muhammad Hussain, Iskander, Peter A, Ahmed, Khalid, Jaber, Fouad, Paz, Merlin, Khan, Ali, Malik, Fahad, Aloysius, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120881/
https://www.ncbi.nlm.nih.gov/pubmed/37090326
http://dx.doi.org/10.7759/cureus.36528
_version_ 1785029259375411200
author Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Ahmed, Khalid
Jaber, Fouad
Paz, Merlin
Khan, Ali
Malik, Fahad
Aloysius, Mark M
author_facet Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Ahmed, Khalid
Jaber, Fouad
Paz, Merlin
Khan, Ali
Malik, Fahad
Aloysius, Mark M
author_sort Zaidi, Syed Muhammad Hussain
collection PubMed
description Acute pancreatitis can result secondary to an inflammatory cascade due to an insult to the pancreatic parenchyma, whether it be from infections, medications, etc. We present a case of a 37-year-old male with acute pancreatitis after being started on Paxlovid, a combination drug containing Nirmatrelvir and Ritonavir, for COVID-19 treatment. Multiple reports in the literature have documented such an association between acute pancreatitis and the protease inhibitor Ritonavir. We suspect that similar results may have taken place that link the initiation of this medication with pancreatic inflammation.
format Online
Article
Text
id pubmed-10120881
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-101208812023-04-22 A Rare Case of Paxlovid-Induced Pancreatitis Zaidi, Syed Muhammad Hussain Iskander, Peter A Ahmed, Khalid Jaber, Fouad Paz, Merlin Khan, Ali Malik, Fahad Aloysius, Mark M Cureus Pathology Acute pancreatitis can result secondary to an inflammatory cascade due to an insult to the pancreatic parenchyma, whether it be from infections, medications, etc. We present a case of a 37-year-old male with acute pancreatitis after being started on Paxlovid, a combination drug containing Nirmatrelvir and Ritonavir, for COVID-19 treatment. Multiple reports in the literature have documented such an association between acute pancreatitis and the protease inhibitor Ritonavir. We suspect that similar results may have taken place that link the initiation of this medication with pancreatic inflammation. Cureus 2023-03-22 /pmc/articles/PMC10120881/ /pubmed/37090326 http://dx.doi.org/10.7759/cureus.36528 Text en Copyright © 2023, Zaidi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Ahmed, Khalid
Jaber, Fouad
Paz, Merlin
Khan, Ali
Malik, Fahad
Aloysius, Mark M
A Rare Case of Paxlovid-Induced Pancreatitis
title A Rare Case of Paxlovid-Induced Pancreatitis
title_full A Rare Case of Paxlovid-Induced Pancreatitis
title_fullStr A Rare Case of Paxlovid-Induced Pancreatitis
title_full_unstemmed A Rare Case of Paxlovid-Induced Pancreatitis
title_short A Rare Case of Paxlovid-Induced Pancreatitis
title_sort rare case of paxlovid-induced pancreatitis
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120881/
https://www.ncbi.nlm.nih.gov/pubmed/37090326
http://dx.doi.org/10.7759/cureus.36528
work_keys_str_mv AT zaidisyedmuhammadhussain ararecaseofpaxlovidinducedpancreatitis
AT iskanderpetera ararecaseofpaxlovidinducedpancreatitis
AT ahmedkhalid ararecaseofpaxlovidinducedpancreatitis
AT jaberfouad ararecaseofpaxlovidinducedpancreatitis
AT pazmerlin ararecaseofpaxlovidinducedpancreatitis
AT khanali ararecaseofpaxlovidinducedpancreatitis
AT malikfahad ararecaseofpaxlovidinducedpancreatitis
AT aloysiusmarkm ararecaseofpaxlovidinducedpancreatitis
AT zaidisyedmuhammadhussain rarecaseofpaxlovidinducedpancreatitis
AT iskanderpetera rarecaseofpaxlovidinducedpancreatitis
AT ahmedkhalid rarecaseofpaxlovidinducedpancreatitis
AT jaberfouad rarecaseofpaxlovidinducedpancreatitis
AT pazmerlin rarecaseofpaxlovidinducedpancreatitis
AT khanali rarecaseofpaxlovidinducedpancreatitis
AT malikfahad rarecaseofpaxlovidinducedpancreatitis
AT aloysiusmarkm rarecaseofpaxlovidinducedpancreatitis

Ejemplares similares