Cargando…

p21 facilitates chronic lung inflammation via epithelial and endothelial cells

Cellular senescence is a stable state of cell cycle arrest that regulates tissue integrity and protects the organism from tumorigenesis. However, the accumulation of senescent cells during aging contributes to age-related pathologies. One such pathology is chronic lung inflammation. p21 (CDKN1A) reg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Levi, Naama, Papismadov, Nurit, Majewska, Julia, Roitman, Lior, Wigoda, Noa, Eilam, Raya, Tsoory, Michael, Rotkopf, Ron, Ovadya, Yossi, Akiva, Hagay, Regev, Ofer, Krizhanovsky, Valery
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120903/ https://www.ncbi.nlm.nih.gov/pubmed/36996500 http://dx.doi.org/10.18632/aging.204622

Ejemplares similares

p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling
por: Yosef, Reut, et al.
Publicado: (2017)

Quantitative identification of senescent cells in aging and disease
por: Biran, Anat, et al.
Publicado: (2017)

Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9
por: Abu-Tair, Lina, et al.
Publicado: (2013)

Senescent cells communicate via intercellular protein transfer
por: Biran, Anat, et al.
Publicado: (2015)

Impaired immune surveillance accelerates accumulation of senescent cells and aging
por: Ovadya, Yossi, et al.
Publicado: (2018)

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
por: Yosef, Reut, et al.
Publicado: (2016)

Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
por: Kolodkin-Gal, Dror, et al.
Publicado: (2022)

Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis
por: Roncato, Francesco, et al.
Publicado: (2021)

Conservation genetics of a rare Gerbil species: a comparison of the population genetic structures and demographic histories of the locally rare Pygmy Gerbil and the common Anderson's Gerbil
por: Rotkopf, Ron, et al.
Publicado: (2010)

Molecular pathways of senescence regulate placental structure and function
por: Gal, Hilah, et al.
Publicado: (2019)

Proteomics analysis of a human brain sample from a mucolipidosis type IV patient reveals pathophysiological pathways
por: Vardi, Ayelet, et al.
Publicado: (2021)

Cell fusion induced senescence
por: Gal, Hilah, et al.
Publicado: (2014)

mTOR signaling orchestrates the expression of cytoprotective factors during cellular senescence
por: Yosef, Reut, et al.
Publicado: (2016)

The default network is causally linked to creative thinking
por: Shofty, Ben, et al.
Publicado: (2022)

Genomic profiling of bovine corpus luteum maturation
por: Kfir, Sigal, et al.
Publicado: (2018)

Differential gene expression and transport functionality in the bundle sheath versus mesophyll – a potential role in leaf mineral homeostasis
por: Wigoda, Noa, et al.
Publicado: (2017)

Cognitive impairment in an animal model of multiple sclerosis and its amelioration by glatiramer acetate
por: Aharoni, Rina, et al.
Publicado: (2019)

Physiological and pathological consequences of cellular senescence
por: Burton, Dominick G. A., et al.
Publicado: (2014)

Multi-Axis Niche Examination of Ecological Specialization: Responses to Heat, Desiccation and Starvation Stress in Two Species of Pit-Building Antlions
por: Rotkopf, Ron, et al.
Publicado: (2012)

Assessment of Nutritional Status and Health Perception among Male Inmates in Israeli Prisons
por: Aharon, Shani Ben, et al.
Publicado: (2023)

Gender Related Differences in Response to “In Favor of Myself” Wellness Program to Enhance Positive Self & Body Image among Adolescents
por: Golan, Moria, et al.
Publicado: (2014)

Mesenchymal soluble factors confer imatinib drug resistance in chronic myelogenous leukemia cells
por: Regev, Ofer, et al.
Publicado: (2020)

Single-Channel EEG Features Reveal an Association With Cognitive Decline in Seniors Performing Auditory Cognitive Assessment
por: Molcho, Lior, et al.
Publicado: (2022)

Baseline spirometry parameters as predictors of airway hyperreactivity in adults with suspected asthma
por: Peled, Michael, et al.
Publicado: (2021)

Senescent cell turnover slows with age providing an explanation for the Gompertz law
por: Karin, Omer, et al.
Publicado: (2019)

Monitoring Distribution Dynamics of EV RNA Cargo Within Recipient Monocytes and Macrophages
por: Alfandari, Daniel, et al.
Publicado: (2022)

The oxytocinergic system mediates synchronized interpersonal movement during dance
por: Josef, Liad, et al.
Publicado: (2019)

The association between creativity and 7R polymorphism in the dopamine receptor D4 gene (DRD4)
por: Mayseless, Naama, et al.
Publicado: (2013)

Expertise in Musical Improvisation and Creativity: The Mediation of Idea Evaluation
por: Kleinmintz, Oded M., et al.
Publicado: (2014)

Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity
por: Regev, Noa, et al.
Publicado: (2009)

Increasing population growth by asymmetric segregation of a limiting resource during cell division
por: Avraham, Nurit, et al.
Publicado: (2013)

Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration
por: de Haan, Diede, et al.
Publicado: (2023)

Hidradenitis Suppurativa International Online Community: Patient Characteristics and a Novel Model of Treatment Effectiveness
por: BARAK-LEVITT, Jen, et al.
Publicado: (2022)

The Organophosphate Paraoxon and Its Antidote Obidoxime Inhibit Thrombin Activity and Affect Coagulation In Vitro
por: Golderman, Valery, et al.
Publicado: (2016)

Nonsense mutation-dependent reinitiation of translation in mammalian cells
por: Cohen, Sarit, et al.
Publicado: (2019)

Inferior olive CRF plays a role in motor performance under challenging conditions
por: Ezra-Nevo, Gili, et al.
Publicado: (2018)

An oligoclonal antibody durably overcomes resistance of lung cancer to third‐generation EGFR inhibitors
por: Mancini, Maicol, et al.
Publicado: (2017)

Combined Effect of Moringa oleifera and Ionizing Radiation on Survival and Metastatic Activity of Pancreatic Cancer Cells
por: Hagoel, Lior, et al.
Publicado: (2019)

Radiocarbon analysis of modern olive wood raises doubts concerning a crucial piece of evidence in dating the Santorini eruption
por: Ehrlich, Yael, et al.
Publicado: (2018)

Discovery of annual growth in a modern olive branch based on carbon isotopes and implications for the Bronze Age volcanic eruption of Santorini
por: Ehrlich, Yael, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ftsgqu3atl798b44dojc5bos4j